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Title:
RRBP1 Expression in Paired Central and Peripheral Astrocytoma Tissue Microarray
Authors:  Yan Li, M.D., Ph.D., Baoshi Han, M.D., Youqiang Cui, M.D., Guangcun Liu, M.D., Ph.D., and Xianzeng Hou, M.D., Ph.D.
  Objective: To develop new therapeutic targets for astrocytoma and explore potential mechanisms regulating astrocytoma relapse.
Study Design:
Expression of RRBP1, MMP9, and Ki-67 was investigated at the center and periphery of astrocytoma tissues.
Results:
RRBP1 expression was higher in peripheral than in central astrocytoma tissues, although the difference was not statistically significant. RRBP1 expression was significantly correlated with that of proliferative marker Ki-67 and invasive marker MMP9.
Conclusion:
These results indicate that high RRBP1 expression may regulate astrocytoma proliferation and invasion. However, further investigation is needed to elucidate the underlying potential mechanisms.
Keywords:  astrocytoma; brain cancer; brain neoplasms, malignant; cell proliferation; glioblastoma; MMP9; matrix metalloproteinase 9; neoplasm invasion; ribosome binding protein 1; ribosomal proteins; RRBP1
   
   
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